NeurosciencebioRxivPreprint
Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease
Kate Inman Tsourmas, Claire Ann Butler, Nellie E. Kwang…·Kim N. Green
This study shows that myeloid-derived β-hexosaminidase supports neuronal lysosomal function and that microglial replacement can reverse Sandhoff disease symptoms.
4 citations