Author

Koleta Michalek

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Karin Jutta MetzneriD· 2 shared Sagnik BhattacharjeeiD· 2 shared Adriana L. HotziD· 1 shared Ali MovasatiiD· 1 shared D. Rodrigues· 1 shared Jurek Andres· 1 shared V. Clerc· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Karin Jutta MetznerORCID

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2 papers

Recent·Most cited

Long terminal repeats influence deletion propensity and genome instability in proviruses across major retroviruses

Sagnik Bhattacharjee, Koleta Michalek, Karin Jutta Metzner

This study shows that retroviral LTRs increase the likelihood of large internal deletions in proviruses, with HIV-1 and HTLV-1 LTRs showing higher deletion rates than HIV-2.

bioRxiv · Oct 13, 2026 · PreprintMicrobiology

DNA Damage Response Proteins Are Involved in the Formation of Defective HIV-1 Proviruses

Koleta Michalek, Sagnik Bhattacharjee, Ali Movasati, V. Clerc, Jurek Andres, Adriana L. Hotz, D. Rodrigues, Karin Jutta Metzner

This study identifies DNA damage response proteins that influence the formation of defective HIV-1 proviruses through CRISPR screens and functional validation.

bioRxiv · Jun 1, 2026 · PreprintMolecular Biology