Author

Sagnik Bhattacharjee

University of ZurichORCID 0009-0004-1556-4420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Karin Jutta MetzneriD· 2 shared Koleta Michalek· 2 shared Adriana L. HotziD· 1 shared Ali MovasatiiD· 1 shared D. Rodrigues· 1 shared Jurek Andres· 1 shared V. Clerc· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Karin Jutta MetznerORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 13, 2026

Long terminal repeats influence deletion propensity and genome instability in proviruses across major retroviruses

Sagnik Bhattacharjee, Koleta Michalek, Karin Jutta Metzner

This study shows that retroviral LTRs increase the likelihood of large internal deletions in proviruses, with HIV-1 and HTLV-1 LTRs showing higher deletion rates than HIV-2.

DOI 10.64898/2026.10.12.758617

humanexperimental assay

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Molecular BiologybioRxivPreprintJun 1, 2026

DNA Damage Response Proteins Are Involved in the Formation of Defective HIV-1 Proviruses

Koleta Michalek, Sagnik Bhattacharjee, Ali Movasati…·Karin Jutta Metzner

This study identifies DNA damage response proteins that influence the formation of defective HIV-1 proviruses through CRISPR screens and functional validation.

1 citation

humanCRISPR screen

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