A dynamic 3D polymer model of the Escherichia coli chromosome driven by data from optical pooled screening
Dvir Schirman, Konrad Gras, Vinodh K. Kandavalli, Jimmy Larsson, David Fange, Johan Elf
This study uses live-cell imaging of fluorescently labeled loci in E. coli to inform a dynamic polymer model of chromosome organization across the cell cycle, revealing global reorganization of the chromosome structure.
bioRxiv · Oct 30, 2024 · PreprintSystems Biology