Axel Truedson

Molecular kinetics dictate population dynamics in CRISPR-based plasmid defense

The paper uses time-lapse imaging to study CRISPR-Cas dynamics in bacterial plasmid defense, finding that Cascade provides partial plasmid clearance with tradeoffs between clearance and cell growth.

The 3D point spread function can be autoencoded in latent space

This paper shows that the 3D point spread function of a fluorescent emitter can be directly accessed in the latent space of an autoencoder trained on sample images without z-reference data.