Author

Krista N. Thompson

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Antonio J. Ortega· 2 shared Gracen E. CollieriD· 2 shared John D. HullemaniD· 2 shared Steffi Daniel· 2 shared Bruce A. PosneriD· 1 shared Emily L. Baker· 1 shared Hasan ZakiiD· 1 shared Marian Renwick· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Antonio J. Ortega

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2 papers

Recent·Most cited

Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation

Antonio J. Ortega, Steffi Daniel, Marian Renwick, Pravallika Kambhampati, Krista N. Thompson, Gracen E. Collier, Emily L. Baker, Hasan Zaki, John D. Hulleman

This study shows that removing Nlrp3 reduces basal laminar deposits in both a genetic mouse model and wild-type mice, suggesting a role for Nlrp3 in AMD pathology.

Cell Death and Disease · Nov 6, 2025Peer-reviewedImmunology

GSK3 inhibition reduces ECM production and prevents age-related macular degeneration-like pathology

Sophia M. DiCesare, Antonio J. Ortega, Gracen E. Collier, Steffi Daniel, Krista N. Thompson, Melissa K. McCoy, Bruce A. Posner, John D. Hulleman

The paper shows that GSK3 inhibition reduces fibulin-3 production and prevents AMD-like pathology in a mouse model of ML/DHRD.

JCI Insight · Aug 7, 2024Peer-reviewedNeuroscience