Author

Kristen A. Johnson

Primary ORCID profile (0000-0003-0788-7217 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Kristen A. JohnsoniD1 paper · Scripps Research Institute

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 1

Frequent Co-Authors

Bernard S. GerstmaniD· 2 shared Melissa R. Budicini· 2 shared Nisha Bhattarai· 2 shared Prem P. ChapagainiD· 2 shared Robert V. StaheliniD· 2 shared Carolyn M. Shirey· 1 shared Sarah Catherine B. Baker· 1 shared Sarah Urata· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

Bernard S. GerstmanORCID

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2 papers

Recent·Most cited

PI(4,5)P2 Binding Sites in the Ebola Virus Matrix Protein Modulate Assembly and Budding

Kristen A. Johnson, Melissa R. Budicini, Sarah Urata, Nisha Bhattarai, Bernard S. Gerstman, Prem P. Chapagain, Sheng Li, Robert V. Stahelin

This study identifies two lysine-rich regions in VP40 that bind PI(4,5)P2, stabilizing oligomers necessary for EBOV budding and assembly, with quercetin inhibiting this process.

bioRxiv · Jun 7, 2018 · PreprintMicrobiology

Mutation of Ebola Virus Matrix Protein Cysteine Residues Increases Binding to Phosphatidylserine through Increased Flexibility of a Lipid Binding Loop

Kristen A. Johnson, Nisha Bhattarai, Melissa R. Budicini, Carolyn M. Shirey, Sarah Catherine B. Baker, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin

This study shows that mutating cysteine residues in Ebola virus VP40 increases its binding to phosphatidylserine membranes, leading to longer virus-like particles and enhanced budding.

bioRxiv · Mar 21, 2018 · PreprintMicrobiology