Author

Sheng Li

Nanfang Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

AnsarullahiD· 1 shared Bernard S. GerstmaniD· 1 shared Haihua Liu· 1 shared Hao HeiD· 1 shared Hash Brown TahaiD· 1 shared J. Matthew MahoneyiD· 1 shared Jing Yang· 1 shared Joshy GeorgeiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

AnsarullahORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Causal network perturbation analysis identifies known and novel type-2 diabetes driver genes

Yue Zhao, Hash Brown Taha, Ansarullah, Kailiang Qian, Parveen Kumar, J. Matthew Mahoney, Hao He, Joshy George, Sheng Li

The paper identifies driver genes for type 2 diabetes using causal network perturbation analysis and single-cell RNA sequencing in mouse models.

bioRxiv · May 22, 2024 · PreprintBioinformatics

Landscape of Dysregulated Placental RNA Editing Associated with Preeclampsia

Xiaoxue Yang, Jing Yang, Xiaozhen Liang, Qian Chen, Sijia Jiang, Haihua Liu, Yue Gao, Zhonglu Ren, Yi-Wu Shi, Sheng Li, 余艳红, Mei Zhong, Xinping Yang

The paper identifies widespread RNA editing dysregulation in placental tissue from preeclampsia patients and links it to altered LEP expression and disease pathogenesis.

Hypertension · Apr 20, 2020Peer-reviewedGenomics

PI(4,5)P2 Binding Sites in the Ebola Virus Matrix Protein Modulate Assembly and Budding

Kristen A. Johnson, Melissa R. Budicini, Sarah Urata, Nisha Bhattarai, Bernard S. Gerstman, Prem P. Chapagain, Sheng Li, Robert V. Stahelin

This study identifies two lysine-rich regions in VP40 that bind PI(4,5)P2, stabilizing oligomers necessary for EBOV budding and assembly, with quercetin inhibiting this process.

bioRxiv · Jun 7, 2018 · PreprintMicrobiology