Secreted cytokines from inflammatory macrophages modulate sex differences in valvular interstitial cells on hydrogel biomaterials
Nicole E. Félix Vélez, Kristi Tu, Peng Guo, Ryan Robert Reeves, Brian A. Aguado
The paper investigates how inflammatory cytokines from macrophages differentially affect male and female valvular interstitial cells on hydrogel biomaterials, revealing sex-specific mechanisms in myofibroblast activation and osteoblast-like differentiation.
Journal of Biomedical Materials Research Part A · Feb 24, 2025Peer-reviewedBioengineering