Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis
Dillon P. Cogan, Alexander M. Soohoo, Muyuan Chen, Yan Liu, Krystal L. Brodsky, Chaitan Khosla
The paper investigates intermodular communication in polyketide biosynthesis using cryo-EM and crosslinking, revealing structural insights for designing hybrid synthases.
Nature Chemical Biology · Aug 23, 2024Peer-reviewedBiochemistry