Accurate prediction of CRISPR editing outcomes in somatic cell lines and zygote with few-shot learning
Weizhong Zheng, Lu Yu, Guoliang Wang, Shaoxian Cao, Kuan-Li Ho, Jun Song, Chen Cheng, Joshua W. K. Ho, Xueqing Liu, Meng Wu, Zhonghua Liu, Huili Wang, Pentao Liu, Guocheng Lan, Yuanhua Huang
This paper introduces inDecay, a few-shot learning system for predicting CRISPR editing outcomes in cell lines and zygotes, achieving high accuracy with minimal data.
bioRxiv · Nov 8, 2024 · PreprintBioinformatics