Guocheng Lan

The paper identifies hypoblasts as the origin of the first blood cells in human and non-human primate embryos, showing they contribute to hemoglobin+ phagocyte-like cells and sustain oxygen levels before heart formation.

This study identifies KIF27 as a key regulator of motile cilia assembly by maintaining transition-zone integrity, revealing its role in ciliary structure and function across species.

This paper introduces inDecay, a few-shot learning system for predicting CRISPR editing outcomes in cell lines and zygotes, achieving high accuracy with minimal data.

The paper introduces CELLO-seq, a long-read RNA sequencing method for single cells, to study TE expression in mouse and human cells, finding locus-specific expression and regulatory heterogeneity.

This paper establishes expanded potential stem cells (EPSCs) from mouse blastomeres and shows they can contribute to both embryo proper and trophoblasts in chimeras.