BiochemistryeLifePeer-reviewed
Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
Ruzbeh Mosadeghi, Kurt M Reichermeier, Martin Winkler…·Radolsav I Enchev
The paper identifies structural and kinetic mechanisms of COP9-Signalosome activation and Nedd8 deconjugation in cullin-RING ubiquitin ligase deneddylation.
DOI 10.7554/elife.12102