Inhibition of phosphodiesterase 4B as a novel therapeutic strategy for the treatment of refractory epilepsy
Cassandra D. Kinch, Mitchell Kesler, Deepika Dogra, Kyle Morin, Kingsley Ibhazehiebo, Cristie Grazziotin Noschang, Jong M. Rho, Deborah Marie Kurrasch
SN-2000, a novel PDE4B inhibitor, reduces seizure activity and shows psychiatric-neutral and pro-cognitive properties in preclinical models.
bioRxiv · May 13, 2025 · PreprintNeuroscience