DNA replication stress-induced transcriptome of Human Burkitt lymphoma identifies MBD1 as a novel suppressor of BCL6 rearrangements in germinal center derived B-lymphomagenesis
Santosh Kumar Gothwal, Kyoko Oichai, Jacqueline H. Barlow
This study identifies MBD1 as a suppressor of BCL6 rearrangements in Burkitt lymphoma by regulating DNA methylation and genomic stability during DNA replication stress.
bioRxiv · Mar 13, 2025 · PreprintCancer Biology