Aerocavin is an antibiotic with potent and specific anti-Neisserial activity
Gleb Pishchany, Kyra E Fryling, Vineetha Vasukuttan, Yern‐Hyerk Shin, Tatum D. Mortimer, Yonatan H. Grad, Jon Clardy
This study identifies aerocavin as a potent and specific antibiotic against Neisseria, showing it inhibits bacterial RNA polymerase and has low resistance evolution rates in N. gonorrhoeae.
ACS Infectious Diseases · Jun 12, 2026Peer-reviewedMicrobiology