Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain
Hanjing Yang, Josue Pacheco, Kyumin Kim, Ayub Bokani, Fumiaki Ito, Diako Ebrahimi, Xiaojiang S. Chen
This study identifies how AA/GA dinucleotides downstream of target-C sites enhance APOBEC3G DNA editing through structural and biochemical analysis of rhesus macaque A3G.
bioRxiv · Mar 11, 2024Biochemistry