Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining
Fumiaki Ito, Ziyuan Li, Минахин Леонид Станиславович…·Xiaojiang S. Chen
This study presents cryo-EM structures of Pol theta-helicase domain bound to DNA, revealing its conformational changes during microhomology-mediated end joining.