Author

L. A. Defelipe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

L. H. Otero· 2 shared S. Klinke· 2 shared A. G. Turjanski· 1 shared A. Hernandez Garcia· 1 shared C. Löw· 1 shared C. P. Modenutti· 1 shared D. A. Marti· 1 shared E. J. Sosa· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

L. H. Otero

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis

F. A. Vignale, A. Hernandez Garcia, C. P. Modenutti, E. J. Sosa, L. A. Defelipe, R. R. M. Oliveira, G. L. Nunes, R. M. Acevedo, G. F. Burguener, M. Rossi, P. D. Zapata, D. A. Marti, P. A. Sansberro, G. Oliveira, M. N. Smith, , A. G. Turjanski

The paper reports the yerba mate genome, identifies a unique caffeine biosynthesis pathway, and reveals structural adaptations for convergent evolution of caffeine production.

eLife · Jan 8, 2025Peer-reviewedPlant Biology

Deamidation drives molecular aging of the SARS-CoV-2 spike receptor-binding motif

R. Lorenzo, L. A. Defelipe, L. Aliperti, S. Niebling, T. F. Custodio, C. Löw, J. J. Schwarz, K. Remans, P. O. Craig, L. H. Otero, S. Klinke, M. Garcia-Alai, I. E. Sanchez, L. G. Alonso

This study identifies deamidation hotspots in the SARS-CoV-2 spike receptor-binding motif, showing how this post-translational modification affects viral infectivity and immune response over time.

bioRxiv · May 20, 2021Biochemistry

Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level

L. H. Otero, S. Foscaldi, G. T. Antelo, S. Sirigu, S. Klinke, L. A. Defelipe, M. Sanchez-Lamas, G. Battocchio, L. M. G. Chavas, F. A. Goldbaum, M. A. Mroginski, J. Rinaldi, H. R. Bonomi

The paper presents atomic-level crystal structures of a full-length bacterial phytochrome in Pr and Pfr states, revealing the signaling mechanism involving chromophore isomerization and structural transitions.

bioRxiv · Feb 16, 2021Biophysics