Deamidation drives molecular aging of the SARS-CoV-2 spike receptor-binding motif
R. Lorenzo, L. A. Defelipe, L. Aliperti, S. Niebling, T. F. Custodio, C. Löw, J. J. Schwarz, K. Remans, P. O. Craig, L. H. Otero, S. Klinke, M. Garcia-Alai, I. E. Sanchez, L. G. Alonso
This study identifies deamidation hotspots in the SARS-CoV-2 spike receptor-binding motif, showing how this post-translational modification affects viral infectivity and immune response over time.
bioRxiv · May 20, 2021Biochemistry