IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection
B. A. Rosa, M. Ahmed, D. K. Singh, J. A. Choreno-Parra, J. Cole, L. A. Jimenez-Alvarez, T. S. Rodriguez-Reyna, B. Singh, O. Golzalez, R. Carrion, L. S. Schlesinger, J. Martin, J. Zuniga, M. Mitreva, S. A. Khader, D. Kaushal
This study identifies transcriptional signatures of IFN signaling and neutrophil degranulation in SARS-CoV-2 infected rhesus macaques and humans, highlighting age-related differences and shared pathways with tuberculosis.
bioRxiv · Aug 6, 2020Immunology