Development of a high-throughput barrier function assay using primary human gut organoids
C. W. Wright, N. Li, L. Shaffer, A. Hill, N. Boyer, S. Alves, S. Venkat, K. Biswas, L. A. Lieberman, S. Mohammadi
The paper develops a high-throughput assay using primary human gut organoids to assess barrier function and response to TNF-α, showing dose-dependent rescue by antagonists.
bioRxiv · Dec 16, 2022 · PreprintImmunology