S. Mohammadi

Evaluating the efficacy of protein quantification methods on membrane proteins

This study evaluates common protein quantification methods for membrane proteins and finds that they underestimate concentrations compared to a newly developed ELISA, which provides reliable results.

Investigating apparent differences between standard DKI and axisymmetric DKI and its consequences for biophysical parameter estimates

This study compares standard and axisymmetric DKI models, finding significant differences in biophysical parameter estimates, particularly for kurtosis and related metrics.

Development of a high-throughput barrier function assay using primary human gut organoids

The paper develops a high-throughput assay using primary human gut organoids to assess barrier function and response to TNF-α, showing dose-dependent rescue by antagonists.

Epistatic effects between amino acid insertions and substitutions mediate toxin-resistance of vertebrate Na+,K+-ATPases

The paper shows how amino acid insertions and substitutions in Na+,K+-ATPase affect toxin resistance in different vertebrate lineages through epistatic interactions.

The action of antimicrobial peptide LL37 is slow but effective against non-growing Escherichia coli cells

This study shows that LL37 antimicrobial peptide acts slower on non-growing E. coli cells but is more potent in killing them over time compared to exponentially growing cells.

Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence

The paper investigates how intramolecular epistasis affects the evolution of CTS-resistant Na,K-ATPases, finding that resistance substitutions have pleiotropic effects independent of sequence divergence.

Raabin-WBC: a large free access dataset of white blood cells from normal peripheral blood

The paper introduces Raabin-WBC, a dataset of white blood cells for machine learning tasks, showing how data diversity impacts model generalization.

Isolation of potential plant growth-promoting bacteria from nodules of legumes grown in arid Botswana soil

The paper isolates plant growth-promoting bacteria from legume nodules in Botswana soils, identifying drought-tolerant species and noting differences in microbial composition between soil and nodule microbiomes.

Concerted evolution reveals co-adapted amino acid substitutions in Na+K+-ATPase of frogs that prey on toxic toads

The paper shows that selection maintains adaptive division-of-labor between tandem duplicates of ATP1A1 in frogs, countering gene conversion to confer toxin resistance.

NODDI-DTI: extracting neurite orientation and dispersionparameters from a diffusion tensor

NODDI-DTI extracts biophysical parameters from DTI data using simplified analytical relations, showing comparable accuracy to full model fitting but with limitations.