Experimental microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid diversification of genome sequence and structure.
G. M. Matos, M. D. Lewis, C. Talavera-Lopez, M. Yeo, E. C. Grisard, L. A. Messenger, M. A. Miles, B. Andersson
This study experimentally evolves Trypanosoma cruzi hybrids, showing tetraploid formation, mutation accumulation, and genome erosion over generations, suggesting adaptive potential through genetic exchange.
bioRxiv · Oct 24, 2021Microbiology