G. Hughes

Contrasting patterns of Asaia sp association with Plasmodium falciparum between field collected Anopheles gambiae and Anopheles coluzzii from Cameroon

This study quantifies Asaia sp. infection in Anopheles mosquitoes from Cameroon and finds no correlation between Asaia and Plasmodium falciparum infection.

Interkingdom interactions shape the fungal microbiome of mosquitoes

This study investigates the fungal microbiome of three mosquito species, finding environmental and host factors influence fungal diversity, with interkingdom interactions affecting fungal colonization.

Microbiome variability of mosquito lines is consistent over time and across environments

The paper shows that mosquito lines maintain distinct microbiomes across different environments, indicating host genetics and environment both shape microbiome composition.

Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes.

This study compares gut transcriptomic responses of mosquitoes to microbiome transplants from field-caught versus laboratory-reared donors, finding greater gene expression variation with field microbiomes.

Virucidal activity of CPC-containing oral rinses against SARS-CoV-2 variants and are active in the presence of human saliva

This study evaluates CPC-containing mouthwashes' virucidal activity against SARS-CoV-2 variants, showing significant inactivation even in the presence of human saliva.

SARS-CoV-2 neutralising antibodies in Dogs and Cats in the United Kingdom

This study reports the first large-scale serological survey of SARS-CoV-2 neutralising antibodies in dogs and cats in the UK, finding low prevalence during the second wave of human infections.

Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouse

This study investigates SARS-CoV-2 variant neuroinvasion in K18-hACE2 mice, finding CNS spread in all variants except Omicron, with microglial activation and immune cell apoptosis observed.

Sequence analysis of SARS-CoV-2 in nasopharyngeal samples from patients with COVID-19 illustrates population variation and diverse phenotypes, placing the in vitro growth properties of B.1.1.7 and B.1.351 lineage viruses in context.

The paper analyzes SARS-CoV-2 sequence variation in patient samples and compares the in vitro growth of B.1.1.7 and B.1.351 variants to other isolates, finding no significant difference in growth for B.1.1.7.

Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351

This study shows that prior SARS-CoV-2 infection in Syrian Golden Hamsters protects against re-exposure to variants B.1.1.7 and B.1.351, suggesting immunity may limit disease from emerging variants.

Mayaro Virus Infection Elicits an Innate Immune Response in Anopheles stephensi

This study examines the transcriptomic and small RNA responses of Anopheles stephensi to Mayaro virus infection, identifying regulated genes, novel miRNAs, and an siRNA response targeting the virus.

Genomic and microscopic evidence of stable high density and maternally inherited Wolbachia infections in Anopheles mosquitoes

The paper identifies high-density, maternally inherited Wolbachia infections in Anopheles mosquitoes using genomic and microscopic evidence, suggesting their potential for biocontrol.

Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.

This study shows that sequential infection with influenza A virus followed by SARS-CoV-2 in mice leads to more severe disease and encephalitis compared to single infections.