A cathepsin C-like protease post-translationally modifies Toxoplasma gondii secretory proteins for optimal invasion and egress.
L. B. Thornton, M. Key, C. Micchelli, A. J. Stasic, S. Kwain, K. Floyd, S. N. J. Moreno, B. N. Dominy, D. C. Whitehead, Z. Dou
This study identifies TgCPC1, a cathepsin C-like protease in Toxoplasma gondii, as essential for the post-translational modification of micronemal proteins required for invasion and egress.
bioRxiv · Jan 21, 2023 · PreprintMicrobiology