Author

S. Kwain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. N. Dominy· 2 shared D. C. Whitehead· 2 shared A. J. Stasic· 1 shared A. Jebet· 1 shared B. Staker· 1 shared C. Micchelli· 1 shared C.-D. Pham· 1 shared E. A. Moseman· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

B. N. Dominy

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

J. E. Milanes, V. C. Yan, C.-D. Pham, F. L. Muller, S. Kwain, K. C. Rees, B. N. Dominy, D. C. Whitehead, S. W. Millward, M. Bolejack, J. Abendroth, I. Q. Phan, B. Staker, E. A. Moseman, X. Zhang, , J. Morris

This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.

bioRxiv · Jan 16, 2024 · PreprintBiochemistry

A cathepsin C-like protease post-translationally modifies Toxoplasma gondii secretory proteins for optimal invasion and egress.

L. B. Thornton, M. Key, C. Micchelli, A. J. Stasic, S. Kwain, K. Floyd, S. N. J. Moreno, B. N. Dominy, D. C. Whitehead, Z. Dou

This study identifies TgCPC1, a cathepsin C-like protease in Toxoplasma gondii, as essential for the post-translational modification of micronemal proteins required for invasion and egress.

bioRxiv · Jan 21, 2023 · PreprintMicrobiology