Author

L. Barakat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Shaw· 1 shared A. Sopeyin· 1 shared B. Vander Wyk· 1 shared C. Radcliffe· 1 shared E. Paintsil· 1 shared H. Allore· 1 shared H. Zapata· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Kumar

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2 papers

Recent·Most cited

Dectin-1 Stimulation Promotes a Distinct Inflammatory Signature in the Setting of HIV-infection and Aging

A. Kumar, J. Wang, H. Zhou, C. Radcliffe, B. Vander Wyk, H. Allore, S. Tsang, L. Barakat, S. Mohanty, H.-y. Zhao, A. Shaw, H. Zapata

This study shows that HIV-positive older adults have a unique inflammatory response to Dectin-1 stimulation, marked by increased cytokines and immune activation.

Aging · Aug 30, 2023Peer-reviewedImmunology

Dysregulation of Sterol Regulatory Element-Binding Protein 2 Gene in HIV Treatment-Experienced Individuals

A. Sopeyin, L. Zhou, M. Li, L. Barakat, E. Paintsil

The paper examines how antiretroviral therapy affects cholesterol biosynthesis in HIV-positive individuals, finding upregulated HMGCR and ABCA1 expression and dysregulation in SREBP-2 and LDLR pathways.

bioRxiv · Aug 21, 2019Pharmacology & Toxicology