The transcriptional regulator Id2 is critical for adipose-resident regulatory T cell differentiation, survival and function
A. B. Frias, E. J. Hyzny, H. M. Buechel, L. Beppu, B. Xie, M. J. Jurczak, L. M. D'Cruz
This study shows that Id2 is essential for the differentiation, survival, and function of adipose-resident regulatory T cells, and its loss leads to systemic inflammation and metabolic issues.
bioRxiv · Mar 27, 2019Immunology