Author

A. B. Frias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. Xie· 2 shared L. M. D'Cruz· 2 shared M. J. Jurczak· 2 shared A. A. Sharma· 1 shared A. C. Poholek· 1 shared A. N. Fooks· 1 shared B. Youngblood· 1 shared C. M. Constantz· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

B. Xie

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HIV-specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions

A. B. Frias, R. L. Rutishauser, A. A. Sharma, T. Mi, C. Zebley, C. M. Constantz, H. A. Abdelsamed, M. Stone, M. P. Busch, S. Deeks, R.-P. Sekaly, B. Youngblood

This study identifies epigenetic and transcriptional features in HIV-specific CD8 T cells from elite controllers that support long-lived effector functions and developmental potential.

bioRxiv · Sep 28, 2021 · PreprintImmunology

Blimp-1 in adipose resident Tregs controls adipocyte beiging and obesity

L. Y. Beppu, X. Qu, G. J. Marrero, A. N. Fooks, A. B. Frias, K. E. Helfrich, I. Sipula, B. Xie, S. C. Watkins, A. C. Poholek, M. J. Jurczak, L. M. D'Cruz

This study shows that Blimp-1 in adipose Tregs suppresses IL-10, reducing beiging and increasing obesity risk, while its ablation improves insulin sensitivity and reduces weight in mice.

bioRxiv · Dec 14, 2019 · PreprintImmunology

The transcriptional regulator Id2 is critical for adipose-resident regulatory T cell differentiation, survival and function

A. B. Frias, E. J. Hyzny, H. M. Buechel, L. Beppu, B. Xie, M. J. Jurczak, L. M. D'Cruz

This study shows that Id2 is essential for the differentiation, survival, and function of adipose-resident regulatory T cells, and its loss leads to systemic inflammation and metabolic issues.

bioRxiv · Mar 27, 2019Immunology