Vapor cannabis exposure generationally affects male reproductive functions in mice
M. Shi, E. M. Langholt, L. C. Butler, M. E. Harvey, E. C. Wheeler, L. Zhao, J. A. MacLean, Y. Oh, E. J. Sabrowsky, S. Yu, S. A. Watson, J. F. Davis, K. Hayashi
This study shows that cannabis vapor exposure in adult male mice reduces sperm count and motility in F0 and F1 generations but not F2, and disrupts spermatogenesis and DNA methylation in F1 testes.
bioRxiv · Aug 22, 2021Pharmacology & Toxicology