Author

Y. Oh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Bioengineering· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:genetic perturbation / CRISPR· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2

Frequent Co-Authors

S. Lee· 4 shared C. H. Kim· 3 shared B.-H. Jun· 2 shared H. Kim· 2 shared J.-W. Huh· 2 shared K.-S. Lim· 2 shared L. W. Gwon· 2 shared V. M. Whitaker· 2 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersPlant Biology

S. Lee

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Adolescent parvalbumin expression in the left orbitofrontal cortex shapes sociability in female mice

Y.-S. Jeon, D. Jeong, H. Kweon, J.-H. Kim, C. Y. Kim, Y. Oh, Y.-H. Lee, C. H. Kim, S.-G. Kim, J.-W. Jeong, E. Kim, S.-H. Lee

This study shows that adolescent social isolation in female mice leads to increased sociability, reduced parvalbumin expression, and decreased social sniffing activity in the left orbitofrontal cortex, highlighting the role of PV+ inhibitory circuits in shaping female social behavior.

bioRxiv · Mar 4, 2022Animal Behavior & Cognition

Highly specific chimeric DNA-RNA guided genome editing with enhanced CRISPR-Cas12a system

H. Kim, W.-j. Lee, C. H. Kim, Y. Oh, L. W. Gwon, H. Lee, W. Song, J. K. Hur, K.-S. Lim, K. J. Jeong, K.-H. Nam, Y.-S. Won, Y. Lee, Y.-H. Kim, J.-W. Huh, , S. H. Lee

The paper enhances CRISPR-Cas12a system specificity and efficiency using a chimeric DNA-RNA guide, achieving 7.41 and 7.60 times improvements respectively.

bioRxiv · Sep 4, 2021Biochemistry

Vapor cannabis exposure generationally affects male reproductive functions in mice

M. Shi, E. M. Langholt, L. C. Butler, M. E. Harvey, E. C. Wheeler, L. Zhao, J. A. MacLean, Y. Oh, E. J. Sabrowsky, S. Yu, S. A. Watson, J. F. Davis, K. Hayashi

This study shows that cannabis vapor exposure in adult male mice reduces sperm count and motility in F0 and F1 generations but not F2, and disrupts spermatogenesis and DNA methylation in F1 testes.

bioRxiv · Aug 22, 2021Pharmacology & Toxicology

Expansion of the prime editing modality with Cas9 from Francisella novicida

Y. Oh, W.-j. Lee, H. Kim, L. W. Gwon, Y.-H. Kim, Y.-H. Park, C. H. Kim, K.-S. Lim, B.-S. Song, J.-W. Huh, S.-U. Kim, B.-H. Jun, C. Jung, S. Lee

This study expands prime editing by linking reverse transcriptase to FnCas9(H969A) nickase, enabling more precise and extended target gene modifications.

bioRxiv · May 25, 2021Bioengineering

Antiviral effect of a nucleic acid hydrolyzing scFv against oseltamivir resistant influenza A virus

Y. Lee, D. Kim, T. Kim, Y. Oh, w.-k. Kim, S. Lee

This study demonstrates that 3D8 scFv has antiviral activity against oseltamivir-resistant influenza A virus in cell and mouse models.

bioRxiv · Feb 19, 2021 · PreprintMicrobiology

Genetic Analysis of Methyl Anthranilate, Mesifurane, Linalool and Other Flavor Compounds in Cultivated Strawberry (Fragaria xananassa)

C. R. Barbey, M. H. Hogshead, B. Harrison, A. E. Schwartz, S. Verma, Y. Oh, S. Lee, K. M. Folta, V. M. Whitaker

This study identifies QTL and candidate genes for flavor compounds in strawberry using multi-omics analyses, revealing novel genes and pathways involved in volatile compound biosynthesis.

bioRxiv · Oct 7, 2020Plant Biology

Allelic Variation of MYB10 is the Major Force Controlling Natural Variation of Skin and Flesh Color in Strawberry (Fragaria spp.) fruit

C. Castillejo, V. Waurich, H. Wagner, R. Ramos, N. Oiza, P. Munoz, J. C. Trivino, J. Caruana, Z. Liu, N. Cobo, M. A. Hardigan, S. J. Knapp, J. G. Vallarino, S. Osorio, C. Martin-Pizarro, , I. Amaya

This study identifies MYB10 allelic variation as the primary driver of natural color variation in strawberry fruit, with specific mutations affecting anthocyanin biosynthesis in both diploid and octoploid species.

bioRxiv · Jun 12, 2020Plant Biology