Author

L. C. Johnson

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Biology Disciplines

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Biochemistry· 2

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1 Organism:human· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

S. S. Patel· 2 shared A. Singh· 1 shared J. Shen· 1 shared M. Farooqui· 1 shared N. Mishra· 1 shared U. Basu· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

S. S. Patel

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2 papers

Recent·Most cited

The N-terminal domain of the human mitochondrial helicase Twinkle has DNA binding activity crucial for supporting processive DNA synthesis by Polymerase γ

L. C. Johnson, A. Singh, S. S. Patel

bioRxiv · Nov 10, 2022Biochemistry

Auto-inhibitory regulation of DNA binding by the C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M

U. Basu, N. Mishra, M. Farooqui, J. Shen, L. C. Johnson, S. S. Patel

This study identifies autoinhibitory mechanisms in Mtf1 and TFB2M where the C-tail region regulates DNA binding activity through intramolecular interactions, which are relieved by RNA polymerase interaction.

bioRxiv · Mar 6, 2020Biochemistry