Author

L. Cagnin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. K. Shalek· 2 shared C. McGuckin· 2 shared J. Kaminski· 2 shared L. S. Kean· 2 shared P. Keskula· 2 shared R. A. Fleming· 2 shared U. Gerdemann· 2 shared V. Tkachev· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. K. Shalek

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Author profile →

2 papers

Recent·Most cited

B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients

J. Kaminski, R. A. Fleming, F. Alvarez-Calderon, C. McGuckin, E. E. Ho, F. Eng, X. Rui, P. Keskula, L. Cagnin, J. Charles, J. Zavistaski, S. P. Margossian, M. A. Kapadia, J. B. Rottman, J. Lane, , U. Gerdemann

The paper identifies a novel mechanism where CAR-T cell therapy activates CD8+ cytotoxic bystander T cells in non-human primates and patients, showing they can kill leukemic cells independently of TCR.

bioRxiv · Sep 28, 2023 · PreprintImmunology

Identification and tracking of alloreactive T cell clones in Rhesus Macaques through the RM-scTCR-Seq platform.

U. Gerdemann, R. A. Fleming, J. Kaminski, C. McGuckin, X. Rui, J. F. Lane, P. Keskula, L. Cagnin, A. K. Shalek, V. Tkachev, L. S. Kean

The paper introduces RM-scTCR-Seq, a method for tracking T cell clones in Rhesus Macaques, and applies it to study GVHD.

bioRxiv · Oct 29, 2021Immunology