Author

J. Charles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. J. Civitello· 2 shared M. P. Mahalila· 2 shared N. C. Starkloff· 2 shared S. Kinung'hi· 2 shared T. Angelo· 2 shared A. Bhaskar· 1 shared A. K. Shalek· 1 shared C. McGuckin· 1 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersEcology

D. J. Civitello

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients

J. Kaminski, R. A. Fleming, F. Alvarez-Calderon, C. McGuckin, E. E. Ho, F. Eng, X. Rui, P. Keskula, L. Cagnin, J. Charles, J. Zavistaski, S. P. Margossian, M. A. Kapadia, J. B. Rottman, J. Lane, , U. Gerdemann

The paper identifies a novel mechanism where CAR-T cell therapy activates CD8+ cytotoxic bystander T cells in non-human primates and patients, showing they can kill leukemic cells independently of TCR.

bioRxiv · Sep 28, 2023 · PreprintImmunology

Mapping of snail intermediate host habitat reveals variability in schistosome and nonschistosome trematode transmission in endemic settings

T. Angelo, N. C. Starkloff, M. P. Mahalila, J. Charles, D. J. Civitello, S. Kinung'hi

This study maps snail habitats and parasite distribution in Tanzania to identify local factors influencing schistosome and nonschistosome transmission.

bioRxiv · Jun 4, 2023 · PreprintEcology

Spatiotemporal variability in transmission risk of human schistosomes and animal trematodes in a seasonally desiccating East African landscape

N. C. Starkloff, T. Angelo, M. P. Mahalila, J. Charles, S. Kinung'hi, D. J. Civitello

The paper investigates seasonal dynamics of schistosome and trematode transmission in East African ponds, finding intermediate pond ephemerality correlates with highest schistosome infection rates.

bioRxiv · May 25, 2023 · PreprintEcology

Rhythm generating mechanisms in rat sino-atrial node and ventricle

J. Charles, L. Nedumaran, S. Raman, E. Vinod, R. Rajasegaran, K. Vadivel, A. Bhaskar, S. Subramani

This study investigates rhythm-generating mechanisms in rat heart tissue, identifying key ion currents involved in sinoatrial and idioventricular rhythms.

bioRxiv · Feb 28, 2023 · PreprintPhysiology