Pre-Germinal Center Interactions with T Cells are Natural Checkpoints to Limit Autoimmune B Cell Responses
K. A. Parham, X. X. S. Tan, D. M. Morelli, L. Chowdhury, H. C. Craig, S. M. Kerfoot
The paper examines T-B cell interactions in response to self-antigen MOG and foreign antigen NP-OVA, finding lower quality interactions with MOG that may represent natural checkpoints to limit autoimmune responses.
bioRxiv · Jul 20, 2022Immunology