HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features.
W. J. Thrift, N. W. Lounsbury, Q. Broadwell, A. Heidersbach, E. Freund, Q. Phung, Y. Abdolazimi, J. Chen, A.-H. Capietto, A.-J. Tong, C. M. Rose, C. Blanchette, J. Lill, B. Haley, L. Delamarre, , S. Jhunjhunwala
HLApollo improves MHC-I peptide presentation prediction with a transformer model, showing better performance than existing methods and offering pan-allelic generalization.
bioRxiv · Dec 8, 2022 · PreprintImmunology