Author

M. Darwish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Blanchette· 3 shared A.-J. Tong· 2 shared C. M. Rose· 2 shared A. A. Cass· 1 shared A. Chang· 1 shared A. J. Heidersbach· 1 shared A. Wallace· 1 shared B. Haley· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

C. Blanchette

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3 papers

Recent·Most cited

Discovery of prevalent, clinically actionable tumor neoepitopes via integrated biochemical and cell-based platforms

H. Gurung, A. J. Heidersbach, M. Darwish, P. Chan, J. Li, M. Beresini, O. Zill, A. Wallace, A.-J. Tong, D. Hascall, E. Torres, A. Chang, K. Lou, Y. Abdolazimi, U. Uche, , C. M. Rose

The paper identifies 84 clinically relevant neoepitope-HLA pairs from 37 shared cancer neoantigens using a combination of biochemical assays and computational methods.

bioRxiv · Oct 27, 2022 · PreprintCancer Biology

Sensitive and quantitative detection of MHC-I displayed neoepitopes using a semi-automated workflow and TOMAHAQ mass spectrometry

S. B. Pollock, C. M. Rose, M. Darwish, R. Bouziat, L. Delamarre, C. Blanchette, J. R. Lill

The paper develops a semi-automated workflow with TOMAHAQ mass spectrometry to detect and quantify MHC-I displayed neoepitopes in various cell lines.

bioRxiv · Dec 16, 2020Cancer Biology

Transposable Element Expression In Tumors Is Associated With Immune Infiltration And Increased Antigenicity

Y. Kong, C. Rose, A. A. Cass, M. Darwish, S. Lianoglou, P. M. Haverty, A.-J. Tong, C. Blanchette, I. Mellman, R. Bourgon, G. John, S. Jhunjhunwala, M. L. Albert, H. Chen-Harris

The paper shows that transposable element expression in tumors correlates with immune infiltration and increased antigenicity, suggesting potential synergy with immunotherapy.

bioRxiv · Aug 9, 2018Cancer Biology