RAD18 opposes transcription-associated genome instability through FANCD2 recruitment
J. Wells, E. Y.-C. Chang, L. Dinatto, J. White, P. Stirling
This study shows RAD18 recruits FANCD2 to suppress R-loops and transcription-replication conflicts, reducing genome instability during DNA replication stress.
bioRxiv · Jun 24, 2022Cell Biology