Cancer associated fibroblasts mitigate the efficacy of the combination treatment of chemotherapy and BCL-xL targeting in triple negative breast cancer cells
L. Nocquet, J. Roul, L. Duarte, M. Campone, P. P. Juin, F. Souaze
This study shows that BCL-xL promotes chemotherapy resistance in TNBC cells, and CAFs reduce the effectiveness of chemotherapy combined with BCL-xL inhibition.
bioRxiv · Sep 26, 2023Cancer Biology