Author

L. E. Farleigh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Albecka· 1 shared C. H. Douse· 1 shared D. M. Prigozhin· 1 shared I. A. Tchasovnikarova· 1 shared P. J. Lehner· 1 shared R. T. Timms· 1 shared S. M. Freund· 1 shared S. Maslen· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Albecka

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1 paper

Recent·Most cited

Periphilin self-association underpins epigenetic silencing by the HUSH complex

D. M. Prigozhin, A. Albecka, C. H. Douse, I. A. Tchasovnikarova, R. T. Timms, L. E. Farleigh, S.-i. Oda, S. M. Freund, S. Maslen, P. J. Lehner, Y. Modis

This study identifies the physicochemical properties of Periphilin required for HUSH complex assembly and epigenetic silencing, showing its N-terminal domain drives aggregation and repressive mark deposition.

bioRxiv · Dec 18, 2019Biochemistry