Author

I. A. Tchasovnikarova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

C. H. Douse· 2 shared P. J. Lehner· 2 shared R. T. Timms· 2 shared Y. Modis· 2 shared A. Albecka· 1 shared D. M. Prigozhin· 1 shared L. E. Farleigh· 1 shared M. Shamin· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

C. H. Douse

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2 papers

Recent·Most cited

BiochemistrybioRxivDec 18, 2019

Periphilin self-association underpins epigenetic silencing by the HUSH complex

D. M. Prigozhin, A. Albecka, C. H. Douse…·Y. Modis

This study identifies the physicochemical properties of Periphilin required for HUSH complex assembly and epigenetic silencing, showing its N-terminal domain drives aggregation and repressive mark deposition.

DOI 10.1093/nar/gkaa785

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivOct 2, 2017

Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

C. H. Douse, S. Bloor, Y. Liu…·Y. Modis

This study investigates how neuropathic mutations in MORC2 disrupt dimerization dynamics and epigenetic silencing through structural changes in the ATPase module.

DOI 10.1038/s41467-018-03045-x

humanstructural biology

𝕏 PostBluesky