Author

L. F. R. Gebert

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

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I. J. MacRae· 1 shared J. Sheu-Gruttadauria· 1 shared Y. Xiao· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiochemistry

I. J. MacRae

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1 paper

Recent·Most cited

Beyond the seed: structural basis for supplementary mircoRNA targeting

J. Sheu-Gruttadauria, Y. Xiao, L. F. R. Gebert, I. J. MacRae

The paper reports the structure of Ago2 bound to a target RNA using both seed and supplementary regions, showing supplementary interactions significantly enhance target affinity.

bioRxiv · Nov 22, 2018Biochemistry