Author

J. Sheu-Gruttadauria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. L. Gao· 1 shared A. Xu· 1 shared C. A. Espinoza· 1 shared I. J. MacRae· 1 shared J. A. Carmona-Negron· 1 shared J. E. Park· 1 shared J. M. Liboy-Lugo· 1 shared L. F. R. Gebert· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. L. Gao

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2 papers

Recent·Most cited

Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

J. M. Liboy-Lugo, C. A. Espinoza, J. Sheu-Gruttadauria, J. E. Park, A. Xu, Z. Jowhar, A. L. Gao, J. A. Carmona-Negron, T. Wittmann, N. Jura, S. N. Floor

The paper identifies key residues in G3BPs that drive stress granule formation and gene expression changes under cellular stress, with G3BP2B showing specific roles in ER stress.

bioRxiv · Feb 6, 2024Cell Biology

Beyond the seed: structural basis for supplementary mircoRNA targeting

J. Sheu-Gruttadauria, Y. Xiao, L. F. R. Gebert, I. J. MacRae

The paper reports the structure of Ago2 bound to a target RNA using both seed and supplementary regions, showing supplementary interactions significantly enhance target affinity.

bioRxiv · Nov 22, 2018Biochemistry