Author

L. Fiddes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

E. Aikawa· 2 shared J. E. Fish· 2 shared K. L. Howe· 2 shared K. Prajapati· 2 shared M. C. Blaser· 2 shared N. J. Galant· 2 shared R. Wu· 2 shared S. A. Singh· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

E. Aikawa

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Author profile →

2 papers

Recent·Most cited

Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis

S. Raju, M. E. Turner, C. Cao, M. Abdul-Samad, N. Punwasi, M. C. Blaser, R. M. Cahalane, S. R. C. Botts, K. Prajapati, S. Patel, R. Wu, D. Gustafson, N. J. Galant, L. Fiddes, M. Chemaly, , K. L. Howe

This study identifies EV-driven endothelial communication in human carotid atherosclerosis, showing increased angiogenic activity in symptomatic plaques.

bioRxiv · Jun 21, 2024 · PreprintCell Biology

Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall

S. Raju, S. R. Botts, M. C. Blaser, K. Prajapati, T. W. W. Ho, C. Ching, N. J. Galant, L. Fiddes, R. Wu, C. L. Clift, T. Pham, W. L. Lee, S. A. Singh, E. Aikawa, J. E. Fish, K. L. Howe

This study shows endothelial cells release distinct extracellular vesicles to reprogram monocytes and smooth muscle cells in circulation and vessel wall.

bioRxiv · Apr 28, 2023 · PreprintCell Biology