Author

L. Flamand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Gravel· 3 shared V. Collin· 2 shared A. Blondeau· 1 shared A. Fogdell-Hahn· 1 shared A. Fradet-Turcotte· 1 shared A. K. Hedstrom· 1 shared A. Michel· 1 shared B. B. Kaufer· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

A. Gravel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 type I Interferon modulation by non structural proteins 1 and 2

L. Flamand, E. Lacasse, I. Dubuc, I. Allaeys, L. Gudimard, A. Gravel, E. Boilard

This study investigates how SARS-CoV-2 and its variants modulate type I interferon responses through non-structural proteins 1 and 2, showing differential effects on IFN production and NF-κB-driven inflammation.

bioRxiv · Jun 9, 2022 · PreprintMicrobiology

The immediate early protein 1 of human herpesvirus 6B counteracts ATM activation in an NBS1-dependent manner

V. Collin, E. Biquand, V. Tremblay, E. G. Lavoie, J. Dessapt, A. Blondeau, A. Gravel, L. Flamand, A. Fradet-Turcotte

This paper shows that HHV-6B IE1 inhibits ATM activation at double-strand breaks via NBS1 interaction, leading to genomic instability and affecting viral replication.

bioRxiv · Jul 31, 2021 · PreprintMicrobiology

Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis

E. Engdahl, R. Gustafsson, J. Huang, M. Bistrom, I. Lima Bomfim, P. M. Stridh, M. Khademi, J. Butt, N. Brenner, A. Michel, D. Jons, M. Hortlund, L. Alonso-Magdalena, A. K. Hedstrom, L. Flamand, , A. Fogdell-Hahn

The paper investigates the association between serological responses to HHV-6A and HHV-6B and multiple sclerosis risk, finding increased risk with HHV-6A antibodies and interaction with EBV.

bioRxiv · Aug 28, 2019Immunology

Modulation and recruitment of TRF2 at viral telomeres during human herpesvirus 6A/B infection

S. Gilbert-Girard, A. Gravel, V. Collin, D. J. Wight, B. B. Kaufer, E. Lazzerini, L. Flamand

This study shows HHV-6A/B infections increase telomeric signals and recruit TRF2 to viral telomeres, suggesting a role for shelterin proteins in viral integration.

bioRxiv · Jan 9, 2019 · PreprintMicrobiology