Mechanism of praziquantel action at a parasitic flatworm ion channel
S.-K. Park, L. Friedrich, N. A. Yahya, C. Rohr, E. G. Chulkov, D. Maillard, F. Rippmann, T. Spangenberg, J. S. Marchant
This study identifies the mechanism by which praziquantel activates a specific ion channel in parasitic flatworms, explaining its efficacy against some species but not others.
bioRxiv · Mar 9, 2021Pharmacology & Toxicology