Author

T. Spangenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Cameron· 1 shared C. D. Huston· 1 shared C. Rohr· 1 shared D. Maillard· 1 shared D. W. Griggs· 1 shared E. G. Chulkov· 1 shared E. Stebbins· 1 shared F. Rippmann· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. C. Cameron

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised mice

J. E. Teixeira, M. Gasonoo, P. Miller, J. Ajiboye, A. C. Cameron, E. Stebbins, S. D. Campbell, D. W. Griggs, T. Spangenberg, M. J. Meyers, C. D. Huston

This study identifies potent PDE-V inhibitors effective against Cryptosporidium parvum in immunocompromised mice, with minimal off-target effects.

bioRxiv · Sep 26, 2023 · PreprintMicrobiology

Mechanism of praziquantel action at a parasitic flatworm ion channel

S.-K. Park, L. Friedrich, N. A. Yahya, C. Rohr, E. G. Chulkov, D. Maillard, F. Rippmann, T. Spangenberg, J. S. Marchant

This study identifies the mechanism by which praziquantel activates a specific ion channel in parasitic flatworms, explaining its efficacy against some species but not others.

bioRxiv · Mar 9, 2021Pharmacology & Toxicology