Cancer BiologyPLOS ONEPeer-reviewed
Impact of MMP-2 and MMP-9 activation on wound healing, tumor growth and RACPP cleavage
L. G. Ellies, D. V. Hingorani, C. N. Lippert…·M. A. Whitney
This study investigates the role of MMP-2/-9 in wound healing and tumor progression using double knockout mice, finding that host macrophages, not tumor cells, are the main source of MMP-2/-9 activity in tumors.
DOI 10.1371/journal.pone.0198464