Carcinoma associated mesenchymal stem cells promote ovarian cancer metastasis by increasing tumor heterogeneity through direct mitochondrial transfer
C. Pressimone, L. G. Frisbie, E. Dyer, R. Baruwal, G. Gorecki, Z. Javed, C. St. Croix, S. C. Watkins, M. Calderon, H. I. Atiua, N. Hempel, A. T. Pearson, L. Coffman
This study shows carcinoma-associated mesenchymal stem cells promote ovarian cancer metastasis by transferring mitochondria to cancer cells, increasing tumor heterogeneity and enhancing survival.
bioRxiv · Sep 21, 2022 · PreprintCancer Biology